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Andrea Holmes

Andrea Holmes


Phone Number: 402.826.6762
Department: Chemistry
Office: LI229
Email: [email protected]
Primary Campus: Crete
Credentials: BS, MS, PHD


Andrea E. Holmes, Ph.D., obtained her doctorate degree in organic chemistry at New York University and her post-doctorate at Columbia University where she held a national research fellowship through the Department of Chemistry and the College of Physicians & Surgeons in New York. She also holds courtesy associate professorship appointments at the University of Nebraska in Lincoln and the University of Nebraska Medical Center (UNMC) in Omaha, Nebraska.

Her research interests are in drug detection methods, sensor design, organic synthesis and analysis of natural and synthetic compounds, designing nano-detection arrays for small molecules, conformational discrimination of biological molecules using circular dichroism, colorimetric detection of bacterial infections, and the synthesis of optical fluorescent brighteners.

Dr. Holmes has served as the President of the Nebraska American Chemical Society. She has received several distinguished national honors, including the National Research Service Award from the National Institutes of Health, the National Science Foundation Presidential Early Career Award, and the Henry Dreyfus Teacher Scholar Award. She served as an investigator and an executive management member on multiple funded projects involving nanotechnology, including a $20-million National Science Foundation Research Infrastructure Improvement award for nanohybrid materials research for novel detection technologies, including drug detection.

Dr. Holmes has acquired multi-million funding, including National Institutes of Health funding to implement cutting-edge research involving novel sensor design methods for in field deployment applications, such as law enforcement and Drug Enforcement Agency officers. Dr. Holmes also serves an expert consultant and investigator for Ansera Analytics on a project that is funded by the Department of Defense (Project title: Chemical Biological Radiological Nuclear and Explosives (CBRNE) Reconnaissance Sampling Kit).

My Research

Team Science and Outreach

Dr. Andrea Holmes published a book chapter in "What works in team science and outreach" by Cabra, J., Figliotti, J., & Burnett, A. (2018). Buffalo, NY: Knowinnovation Inc. Pages 95-105. The book chapter discusses the experiences of Dr. Holmes while she worked as a management team leader in the Center for Nanohybrid Materials at UNL as part of a statewide $20Million Research and Infrastructure Grant (EPSCoR). The electronic version of the book is attached.

Download a copy of What Works in Team Science and Outreach.

Selected Publications

  1. Michael J Kangas*, David Symonsbergen and Andrea E. Holmes, "A New Possible Alternative Colorimetric Drug Detection Test for Fentanyl" Organic and Medicinal Chemistry, 4, 4, ISSN: 2474-7610, 2017.
  2. Helena Valquier-Flynn, Christina L. Wilson, Andrea E. Holmes, and Christopher D. Wentworth. "Growth rate of Pseudomonas aeruginosa biofilms on slippery butyl methacrylate-co-ethylene dimethacrylate (BMA-EDMA), glass, and polycarbonate surfaces". Journal of Biotechnology & Biomaterials. 7:274. 2017 DOI: 10.4172/2155-952X274.
  3. Christina Wilson, Rachel Lukowicz, Stefan Merchant, Helena Valquier-Flynn, Jeniffer Caballero, Jasmin Sandoval, Macduff Okuom, Christopher Huber, Tessa Durham Brooks, Erin Wilson, Barbara Clement, Christopher D. Wentworth, and Andrea E. Holmes. "Quantitative and Qualitative Assessment Methods for Biofilm Growth: A mini-review" submitted to Research and Review: Journal of Engineering and Technology, 6 (4), 2017.
  4. M. J. Kangas, R. M. Burks, J. Atwater, R. M. Lukowicz, B. Garver, A. E. Holmes, "Comparative Chemometric Analysis for Classification Acids and Bases via a Colorimetric Sensor Array" accepted to Journal of Chemometrics, 2017:e2961.
  5. Truc H. Doan,Tu A. Doan, Michael J. Kangas, Christina L. Wilson, Andrea E. Holmes, Erin L. Doyle, and Tessa L. Durham Brooks. A non-destructive imaging method for the temporal and spatial colorimetric detection of free amines on maize root surfaces. Frontiers in Plant Science, 8, 1513, 2017.
  6. Uwe Bog, Andres de los Santos Pereira, Summer L. Mueller, Shana Havenridge, Viviana Parrillo, Michael Bruns, Andrea E. Holmes, Cesar Rodriguez-Emmenegger, Harald Fuchs, and Michael Hirtz. ACS Applied Materials & Interfaces 2017 9 (13), 12109-12117 DOI: 10.1021/acsami.7b01184
  7. M. J. Kangas, R. M. Burks, J. Atwater, R. M. Lukowicz, P. Williams, A. E. Holmes, "Colorimetric Sensor Arrays for the Detection and Identification of Chemical Weapons and Explosives." Crit. Rev. Anal. Chem., 2017, VOL. 47, NO. 2, 138-153.